SAP18 Antibody - N-terminal region - HRP
Referencia ARP31468_P050-HRP
embalaje : 100ul
Marca : Aviva Systems Biology
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Teléfono : +1 850 650 7790
SAP18 Antibody - N-terminal region : HRP (ARP31468_P050-HRP)
| Datasheets/Manuals | Printable datasheet for anti-SAP18 (ARP31468_P050-HRP) antibody |
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| Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
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| Product Format | Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Conjugation | HRP: Horseradish Peroxidase |
| Application | WB |
| Reconstitution and Storage | All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
| Immunogen | The immunogen is a synthetic peptide directed towards the N-terminal region of Human SAP18 |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93% |
| Peptide Sequence | Synthetic peptide located within the following region: ESRVTQEEIKKEPEKPIDREKTCPLLLRVFTTNNGRHHRMDEFSRGNVPS |
| Concentration | 0.5 mg/ml |
| Blocking Peptide | For anti-SAP18 (ARP31468_P050-HRP) antibody is Catalog # AAP31468 |
| Gene Symbol | SAP18 |
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| Gene Full Name | Sin3A-associated protein, 18kDa |
| Alias Symbols | SAP18P, 2HOR0202 |
| NCBI Gene Id | 10284 |
| Protein Name | Histone deacetylase complex subunit SAP18 |
| Description of Target | Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. SAP18 is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. |
| Uniprot ID | O00422 |
| Protein Accession # | NP_005861 |
| Nucleotide Accession # | NM_005870 |
| Protein Size (# AA) | 153 |
| Molecular Weight | 16kDa |
| Protein Interactions | INCA1; RBM39; UBC; RNF2; SUZ12; BMI1; CSNK2A2; MAGOH; EIF4A3; VCP; NFIA; SEPT2; MYO1C; IK; HNRNPU; HNRNPC; GTF3C1; SEPT7; CDC5L; U2AF1; SNRPD2; SMARCC2; SMARCB1; SRSF7; SRSF5; SRSF3; SRSF1; SAFB; S100A9; PSAP; NHP2L1; TPR; TFPI; SURF4; SSRP1; SSR3; LOC255 |
