Rp-dGTPαS [80902-29-0]
Referencia NB-64-87150-50mg
embalaje : 50mg
Marca : Neo Biotech
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Teléfono : +1 850 650 7790
Rp-dGTPαS (Synonyms: Rp-dGTP-α-S)
Catalog No. T84664 Copy Product Info
Rp-dGTPαS, an enantiomer of the dNTPαS nucleotide, serves as the substrate for SAMHD1, a critical regulator of cellular dNTP levels that curtails the replication of viruses (HIV-1, etc.) in CD4+ myeloid lineage and resting T cells. The SAMHD1 tetrameric complex facilitates the hydrolysis of Rp-dGQTPαS into 2'-deoxynucleosides and triphosphates [1].
Rp-dGTPαS
Copy Product InfoSynonyms Rp-dGTP-α-S
Rp-dGTPαS, an enantiomer of the dNTPαS nucleotide, serves as the substrate for SAMHD1, a critical regulator of cellular dNTP levels that curtails the replication of viruses (HIV-1, etc.) in CD4+ myeloid lineage and resting T cells. The SAMHD1 tetrameric complex facilitates the hydrolysis of Rp-dGQTPαS into 2'-deoxynucleosides and triphosphates [1].
Cas No. 80902-29-0
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Rp-dGTPαS, an enantiomer of the dNTPαS nucleotide, serves as the substrate for SAMHD1, a critical regulator of cellular dNTP levels that curtails the replication of viruses (HIV-1, etc.) in CD4+ myeloid lineage and resting T cells. The SAMHD1 tetrameric complex facilitates the hydrolysis of Rp-dGQTPαS into 2'-deoxynucleosides and triphosphates [1]. |
| Synonyms | Rp-dGTP-α-S |
| Molecular Weight | 523.25 |
| Formula | C10H16N5O12P3S |
| Cas No. | 80902-29-0 |
| Smiles | O=C1C2=C(N(C=N2)[C@@H]3O[C@H](COP(OP(OP(=O)(O)O)(=O)O)(=O)S)[C@@H](O)C3)NC(N)=N1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |