PRDX2 Antibody - middle region - Biotin
Referencia ARP48281_P050-Biotin
embalaje : 100ul
Marca : Aviva Systems Biology
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PRDX2 Antibody - middle region : Biotin (ARP48281_P050-Biotin)
| Datasheets/Manuals | Printable datasheet for anti-PRDX2 (ARP48281_P050-Biotin) antibody |
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| Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Sheep, Yeast, Zebrafish |
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| Product Format | Liquid. Purified antibody supplied in 1x PBS buffer. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Conjugation | Biotin |
| Application | IHC, WB |
| Additional Information | IHC Information: Paraffin embedded liver tissue, tested with an antibody dilution of 5 ug/ml. |
| Reconstitution and Storage | All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
| Immunogen | The immunogen is a synthetic peptide directed towards the middle region of human PRDX2 |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 79%; Rat: 100%; Sheep: 100%; Yeast: 92%; Zebrafish: 79% |
| Peptide Sequence | Synthetic peptide located within the following region: VLGVSVDSQFTHLAWINTPRKEGGLGPLNIPLLADVTRRLSEDYGVLKTD |
| Concentration | 0.5 mg/ml |
| Blocking Peptide | For anti-PRDX2 (ARP48281_P050-Biotin) antibody is Catalog # AAP48281 (Previous Catalog # AAPY01650) |
| Sample Type Confirmation | PRDX2 is supported by BioGPS gene expression data to be expressed in HeLa |
| Reference | Fang,J., (2007) Proc. Natl. Acad. Sci. U.S.A. 104 (47), 18742-18747 |
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| Gene Symbol | PRDX2 |
| Gene Full Name | Peroxiredoxin 2 |
| Alias Symbols | PRP, TSA, PRX2, PTX1, TPX1, NKEFB, PRXII, TDPX1, NKEF-B, HEL-S-2a |
| NCBI Gene Id | 7001 |
| Protein Name | Peroxiredoxin-2 |
| Description of Target | PRDX2 is a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. It may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. The crystal structure of this protein has been resolved to 2.7 angstroms.This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. The crystal structure of this protein has been resolved to 2.7 angstroms. Transcript variants encoding distinct isoforms have been identified for this gene. |
| Uniprot ID | P35704 |
| Protein Accession # | NP_005800 |
| Nucleotide Accession # | NM_005809 |
| Protein Size (# AA) | 198 |
| Molecular Weight | 22kDa |
| Protein Interactions | UBC; NEDD8; IPO11; CACYBP; PPP2R5D; PRDX1; METTL1; HECW2; ESR1; RAD52; NLGN3; CD320; COPS5; PRDX4; YWHAZ; VCAM1; UTY; SAT1; ITGA4; FN1; CA4; BAD; TPM3P4; TIPRL; TMEM9; RNF32; URM1; RIF1; EXOC6; CYCS; ECSIT; PRDX5; IFIT5; MAST1; PARK7; SEC23IP; CDC37; PRDX |
