Phenytoin [57-41-0]
Referencia M5875-100mg
embalaje : 100mg
Marca : AbMole Bioscience
Contact local distributor :
Teléfono : +1 850 650 7790
All AbMole products are for research use only, cannot be used for human consumption.
Diphenylhydantoin; 5,5-Diphenylhydantoin
Quality Control & Documentation
Biological Activity
Phenytoin (5,5-Diphenylhydantoin) is a potent Voltage-gated Na+ channels (VGSCs) blocker. Phenytoin reduces breast tumour growth and metastasis in mice, and it also has antiepileptic activity. Phenytoin has been shown to activate PXR and subsequently influence the expression of PXR target genes.
Chemical Information
| Molecular Weight | 252.27 |
| Formula | C15H12N2O2 |
| CAS Number | 57-41-0 |
| Solubility (25°C) | DMSO 50 mg/mL |
| Storage | Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
References
[1] Franco V, et al. Expert Opin Drug Metab Toxicol. CYP2C9 polymorphisms and phenytoin metabolism: implications for adverse effects.