PE-Cy7 Anti-Mouse CD38 Antibody(NIMR5)

Referencia PC7-30020-100T

embalaje : 100T

Marca : FineTest

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Teléfono : +1 850 650 7790

Synonyms:2'-phospho-cyclic-ADP-ribose transferase|ADP-ribosyl cyclase 1|ADPRC 1|CD38|NIM-R5 antigen antibody
Catalogue No.:PC7-30020Reactivity:Mouse
Host:RatTested Application:FC
Clonality:MonoclonalIsotype:IgG2a, κ
Inquiry
Dispatch Time: About 3 working days
Product Name
PE-Cy7 Anti-Mouse CD38 Antibody(NIMR5)
Catalogue No.
PC7-30020
Form
liquid
Conjugation
PE-Cy7
Conjugation Information
PE-Cy7 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 775 nm (e.g., a 780/60 nm bandpass filter).
Clonality
Monoclonal
Isotype
IgG2a, κ
Clone ID
NIMR5
Storage
PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Alternative Names
2'-phospho-cyclic-ADP-ribose transferase|ADP-ribosyl cyclase 1|ADPRC 1|CD38|NIM-R5 antigen antibody
UniProt ID
P56528
Application
Tested Applications
FC
Recommended dilution
Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Validated Images
C57BL/6 murine splenocytes are stained with PE-Cy7 Anti-Mouse CD38 Antibody (filled gray histogram) or Rat IgG2a Isotype Control PE (black histogram).
Background
CD38 is a 42 kD glycoprotein, also known as T10. It is an ADP-ribosyl hydrolase, expressed on B cells, NK cells, a subset of T cells, brain, muscle, and kidney. In mouse, CD38 expression is downregulated on germinal center B cells and plasma cells, whereas this is not the case for humans. By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, as well as adhesion and metabolism of cADPR and NAADP. CD31 is the ligand of CD38.

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