PACS1 Antibody - C-terminal region - HRP
Referencia ARP64806_P050-HRP
embalaje : 100ul
Marca : Aviva Systems Biology
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Teléfono : +1 850 650 7790
PACS1 Antibody - C-terminal region : HRP (ARP64806_P050-HRP)
| Datasheets/Manuals | Printable datasheet for anti-PACS1 (ARP64806_P050-HRP) antibody |
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| Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
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| Product Format | Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Conjugation | HRP: Horseradish Peroxidase |
| Application | WB |
| Reconstitution and Storage | All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100% |
| Peptide Sequence | Synthetic peptide located within the following region: ALAIVGSPNSPYGDVIGLQVDYWLGHPGERRREGDKRDASSKNTLKSVFR |
| Concentration | 0.5 mg/ml |
| Blocking Peptide | For anti-PACS1 (ARP64806_P050-HRP) antibody is Catalog # AAP64806 |
| Gene Symbol | PACS1 |
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| Gene Full Name | Phosphofurin acidic cluster sorting protein 1 |
| Alias Symbols | SHMS, MRD17 |
| NCBI Gene Id | 55690 |
| Protein Name | Phosphofurin acidic cluster sorting protein 1 |
| Description of Target | This gene encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance. |
| Uniprot ID | Q6VY07 |
| Protein Accession # | AAH55288 |
| Nucleotide Accession # | NM_018026 |
| Protein Size (# AA) | 575 |
| Molecular Weight | 62kDa |
| Protein Interactions | UBC; GGA3; CSNK2A1; FGFR1OP; PPP2CA; VAMP4; CLCN7; PPP2CB; PKD2; JUN; IGF2R; FURIN; TRPV4; nef; |
