Biological Activity

NADPH tetrasodium salt is a cofactor, used to donate electrons and a hydrogens to reactions catalyzed by some enzymes. NADPH tetrasodium salt functions as an important cofactor in a variety of metabolic and biosynthetic pathways. NADPH tetrasodium salt plays a vital role in the biosynthesis of agents, chiral alcohols, fatty acids and biopolymers, while also being required for lipid biosynthesis, biomass formation, and cell replication.

NADPH tetrasodium salt is an endogenous inhibitor of ferroptosis.

NADPH tetrasodium salt is also essential for the neutralization of the dangerously high levels of reactive oxygen species (ROS) generated by increased metabolic activity.

Product Citations

• 

  Patent. EP4450498A1 2024 Oct 23.

  Patent. EP4450498A1
  NADPH tetrasodium salt purchased from AbMole

• 

  Patent. TW202327591A 2023 Jul 16.

  Patent. TW202327591A
  NADPH tetrasodium salt purchased from AbMole

Chemical Information

Molecular Weight	833.35
Formula	C21H26N7Na4O17P3
CAS Number	2646-71-1
Solubility (25°C)	Water: ≥ 25 mg/mL
Storage	Powder          -20°C   3 years ;  4°C   2 years In solvent       -80°C   6 months ;  -20°C   1 month

References

[1] Adio J Akamo, et al. Naringin prevents cyclophosphamide-induced erythrocytotoxicity in rats by abrogating oxidative stress

[2] Yongbin Ye, et al. High-resolution mass spectrometry-based approach for the identification and profiling of the metabolites of taletrectinib formed in liver microsomes

[3] Jie Liu, et al. Novel molecularly imprinted polymer (MIP) multiple sensors for endogenous redox couples determination and their applications in lung cancer diagnosis

[4] R Wang, et al. Imidacloprid is hydroxylated by Laodelphax striatellus CYP6AY3v2

[5] Shuyun Zhu, et al. Fluorescence detection of glutathione reductase activity based on deoxyribonucleic acid-templated silver nanoclusters