N-Acetylneuraminic acid [131-48-6]
Referencia M7550-500mg
embalaje : 500mg
Marca : AbMole Bioscience
Contact local distributor :
Teléfono : +1 850 650 7790
All AbMole products are for research use only, cannot be used for human consumption.
NANA; Lactaminic acid
Quality Control & Documentation
Biological Activity
N-Acetylneuraminic acid is a nine-carbon, sialic acid monosaccharide commonly found in glycoproteins on cell membranes and in glycolipids such as gangliosides in mammalian cells. Studies suggest that N-Acetylneuraminic acid is useful biologically in neurotransmission, leukocyte extravasation, viral or bacterial infections and carbohydrate-protein recognition.
Protocol (for reference only)
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| Animal models | Sprague-Dawley rats |
| Formulation | - |
| Dosages | 20 mg/kg |
| Administration | i.p. |
Chemical Information
| Molecular Weight | 309.27 |
| Formula | C11H19NO9 |
| CAS Number | 131-48-6 |
| Solubility (25°C) | Water 60 mg/mL |
| Storage | -20°C, sealed |
References
[1] Lee CG, et al. Sci Rep. Inhibition of poly-LacNAc biosynthesis with release of CMP-Neu5Ac feedback inhibition increases the sialylation of recombinant EPO produced in CHO cells.
[2] Wylie AD, et al. J Agric Food Chem. Quantitation of Sialic Acids in Infant Formulas by Liquid Chromatography-Mass Spectrometry: An Assessment of Different Protein Sources and Discovery of New Analogues.
[3] S E Carlson, et al. J Nutr. Oral and intraperitoneal administration of N-acetylneuraminic acid: effect on rat cerebral and cerebellar N-acetylneuraminic acid