Methylene Blue Trihydrate is a competitive inhibitor of glutathione reductase used in combination with antimalarial drugs.

Synonyms:
C.I. Basic Blue 9 Trihydrate; 3,7-Bis(dimethylamino)phenothiazin-5-ium ChlorideTrihydrate; 3,7-Bis(dimethylamino)phenazathionium Chloride Trihydrate; Methylene Blue Trihydrate

CAS No:
7220-79-3

Molecular Formula:
C₁₆H₂₄ClN₃O₃S

Molecular Weight:
373.9

Purity:
98-103% (Assay by titration)

Appearance:
Dark green or blue crystalline powder

Solubility:
Clear blue solution

Copper (Cu):
≤0.02%

Zinc (Zn):
≤0.01%

Arsenic (As):
≤0.0008%

Loss on Drying (@105ºC, 5 hours):
8-18%

Residual Solvents:
To pass test

Residue On Ignition:
≤1.2%

Related Substances:
Azure B: ≤2.5%
Unspecified Impurity: ≤0.1%
Total Impurities: ≤0.5%

Identification:
To pass test

Storage and Stability:
Maybe stored at RT. Stable for 12 months after receipt.