Mc-VC-PAB-SN38 [1801838-28-7]

Referencia NB-64-26715-5mg

embalaje : 5mg

Marca : Neo Biotech

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Teléfono : +1 850 650 7790

Mc-VC-PAB-SN38 (Synonyms: Mc-VC-PAB-SN38)

Catalog No. T39222 Copy Product Info
Purity: 99.22%
Mc-VC-PAB-SN38 consists of a cleavable ADC linker (Mc-VC-PAB) and SN38, which is part of an antibody-coupled reactive molecule commonly used to synthesize antibody-coupled reactive molecules (ADCs) that target sites of action.

Mc-VC-PAB-SN38

Copy Product Info
Synonyms Mc-VC-PAB-SN38

Mc-VC-PAB-SN38 consists of a cleavable ADC linker (Mc-VC-PAB) and SN38, which is part of an antibody-coupled reactive molecule commonly used to synthesize antibody-coupled reactive molecules (ADCs) that target sites of action.

Mc-VC-PAB-SN38
Cas No. 1801838-28-7
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Purity:99.22%
Appearance:Solid
Color:Yellow
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Product Introduction

Bioactivity
Description
Mc-VC-PAB-SN38 consists of a cleavable ADC linker (Mc-VC-PAB) and SN38, which is part of an antibody-coupled reactive molecule commonly used to synthesize antibody-coupled reactive molecules (ADCs) that target sites of action.
In vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.[1]
SynonymsMc-VC-PAB-SN38
Chemical Properties
Molecular Weight991.05
FormulaC51H58N8O13
Cas No.1801838-28-7
SmilesCCc1c2Cn3c(cc4c(COC(=O)[C@@]4(CC)OC(=O)OCc4ccc(NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@@H](NC(=O)CCCCCN5C(=O)C=CC5=O)C(C)C)cc4)c3=O)-c2nc2ccc(O)cc12
Relative Density.1.43 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (50.45 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.0090 mL5.0452 mL10.0903 mL50.4515 mL
5 mM0.2018 mL1.0090 mL2.0181 mL10.0903 mL
10 mM0.1009 mL0.5045 mL1.0090 mL5.0452 mL
20 mM0.0505 mL0.2523 mL0.5045 mL2.5226 mL
50 mM0.0202 mL0.1009 mL0.2018 mL1.0090 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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