L1CAM Antibody
Referencia OABF00891
embalaje : 100ul
Marca : Aviva Systems Biology
Contact local distributor :
Teléfono : +1 850 650 7790
SERPINE1 Recombinant Antibody [10C3] (OACA12304)
| Datasheets/Manuals | Printable datasheet for SERPINE1 Recombinant Antibody [10C3] (OACA12304) |
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| Predicted Species Reactivity | Human |
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| Product Format | Liquid |
| Clonality | Recombinant Monoclonal |
| Conjugation | Unconjugated |
| Application | Enzyme-linked immunosorbent assay, Immunohistochemistry, Western blot |
| Reconstitution and Storage | -20°C or -80°C |
| Immunogen | A synthesized peptide derived from human PAI1 |
| Purification | Affinity Purified |
| Gene Symbol | SERPINE1 |
|---|---|
| Gene Full Name | serpin family E member 1 |
| Alias Symbols | endothelial plasminogen activator inhibitor;PAI;PAI1;PAI-1;PLANH1;plasminogen activator inhibitor 1;serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1;serpin E1;serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1. |
| NCBI Gene Id | 5054 |
| Protein Name | Plasminogen activator inhibitor 1 |
| Description of Target | Serine protease inhibitor. Inhibits TMPRSS7 (PubMed:15853774). Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots (PubMed:8481516, PubMed:9207454, PubMed:17912461). As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading (PubMed:9175705). Acts as a regulator of cell migration, independently of its role as protease inhibitor (PubMed:15001579, PubMed:9168821). It is required for stimulation of keratinocyte migration during cutaneous injury repair (PubMed:18386027). It is involved in cellular and replicative senescence (PubMed:16862142). Plays a role in alveolar type 2 cells senescence in the lung (By similarity). Is involved in the regulation of cementogenic differentiation of periodontal ligament stem cells, and regulates odontoblast differentiation and dentin formation during odontogenesis (PubMed:25808697, PubMed:27046084). |
| Uniprot ID | P05121 |