Kinetin Triphosphate, Tetrasodium Salt (6-Fu-ATP) [1450894-16-2]

Referencia 453052-500ul

embalaje : 500ul

Marca : US Biological

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453052 Kinetin Triphosphate, Tetrasodium Salt (6-Fu-ATP)

Grade
Highly Purified
Shipping Temp
Dry Ice
Storage Temp
-70°C

Kinetin Triphosphate is used in the regulation or bumping up of kinase function for the treatment of Parkinson’s disease.

Synonyms:
[1’,2’,3’,4’,5’-13C5]-Kinetin riboside-5-triphosphate; Kinetin Triphosphate KTP; N6-Furfuryl-ATP; N-(2-Furanylmethyl)-adenosine 5’-(tetrahydrogen Triphosphate); 6-Fu-ATP

CAS No:
1450894-16-2

Molecular Formula:
C₁₅H₂₀N₅O₁₄P₃

Molecular Weight:
587.27 Free acid

Purity (HPLC):
≥95%

Form:
10mM aqueous solution

Absorption max [nm]:
As Reported

Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹]:
As Reported

pH:
As Reported

Storage and Stability:
Store at -70°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Applications
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. ||Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.
References
1. Kleiner, R. E., et al.: Cell, 154:716 (2013) 2. Orr, A. L., et al.: Neurochem. Int., 109:106 (2017) 3. Hertz, N. T., et al.: Cell, 154:737 (2013) 4. Ulrich S. M., Kenski D. M.Shokat K. M., Biochemistry, 42:7915 - 7921 (2003), "Engineering a 'Methionine Clamp' into Src Family Kinases Enhances Specificity toward Unnatural ATP Analogues" 5. Shah K., Liu Y., Deirmengian C.Shokat K. M., Proc. Natl. Acad. Sci. USA, 94:3565 - 3570 (1997), "Engineering Unnatural Nucleotide Specificity for Rous Sarcoma Virus Tyrosine Kinase to Uniquely Label its Direct Substrates"