KAE1 Recombinant Protein
Referencia OPCA03107-100UG
embalaje : 100ug
Marca : Aviva Systems Biology
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KAE1 Recombinant Protein (Baker's yeast) (OPCA03107)
| Datasheets/Manuals | Printable datasheet for KAE1 Recombinant Protein (Baker's yeast) (OPCA03107) |
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| Predicted Species Reactivity | Saccharomyces cerevisiae |
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| Product Format | Liquid or Lyophilized powder |
| Reconstitution and Storage | -20°C or -80°C |
| Peptide Sequence | MVNLNTIPPKNGRDYYIALGLEGSANKLGVGIVKHPLLPKHANSDLSYDCEAEMLSNIRDTYVTPPGEGFLPRDTARHHRNWCIRLIKQALAEADIKSPTLDIDVICFTKGPGMGAPLHSVVIAARTCSLLWDVPLVGVNHCIGHIEMGREITKAQNPVVLYVSGGNTQVIAYSEKRYRIFGETLDIAIGNCLDRFARTLKIPNEPSPGYNIEQLAKKAPHKENLVELPYTVKGMDLSMSGILASIDLLAKDLFKGNKKNKILFDKTTGEQKVTVEDLCYSLQENLFAMLVEITERAMAHVNSNQVLIVGGVGCNVRLQEMMAQMCKDRANGQVHATDNRFCIDNGVMIAQAGLLEYRMGGIVKDFSETVVTQKFRTDEVYAAWRD |
| Source | Yeast |
| Gene Symbol | KAE1 |
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| Gene Full Name | tRNA N6-adenosine threonylcarbamoyltransferase |
| Alias Symbols | Kinase-associated endopeptidase 1, N6-L-threonylcarbamoyladenine synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein KAE1, tRNA N6-adenosine threonylcarbamoyltransferase, tRNA threonylcarbamoyladenosine biosynthesis protein KAE1, YKR038C. |
| NCBI Gene Id | 853910 |
| Protein Name | tRNA N6-adenosine threonylcarbamoyltransferase |
| Description of Target | Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators. |
| Uniprot ID | P36132 |
| Protein Size (# AA) | Full Length |
| Molecular Weight | 44.7 kda |