Interleukin-1 Receptor Antagonist

Referencia 40101P-20

embalaje : 20ug

Marca : Leinco Technologies

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Interleukin1 Receptor Antagonist

Product No.: 40101P

Target
Interleukin1 Receptor Antagonist
Alternate Names
rHuIL1RA
Applications
WB

Antibody Details

Product Details

Reactive Species
Human
State of Matter
Lyophilized
Storage and Handling
Store dessicated below 18°C. After reconstitution, store at 4°C for 27 days and below 18°C for future use. For long term storage of the reconstituted product, addition of 0.1% human serum albumin or bovine serum albumin is recommended. Avoid multiple freeze thaw cycles.
Country of Origin
USA
Shipping
Next Day 28°C
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Description

Specificity
Recombinant Human Interleukin1 Receptor Antagonist
Background
Interleukin1RA is a member of the Interleukin1 (IL1) cytokine family. It inhibits the activities of of IL1 alpha and IL1 beta and modulates a variety of IL 1related immune and inflammatory responses. A polymorphism of this gene is reported to be associated with an increased risk of osteoporotic fractures and gastric cancer.
Function
Inhibits the activity of interleukin1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin1 like activity. Binds functional interleukin1 receptor IL1R1 with greater affinity than dPubMed:7775431}.

References & Citations