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> Insulin (INS) (+Proinsulin) Mouse Monoclonal Antibody [Clone ID: D3E7 (5B6/6)]

Insulin (INS) (+Proinsulin) Mouse Monoclonal Antibody [Clone ID: D3E7 (5B6/6)]

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Referencia BM508

embalaje : 200ug

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Insulin (INS) (+Proinsulin) Mouse Monoclonal Antibody [Clone ID: D3E7 (5B6/6)]

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SKU
BM508
Insulin (INS) (+Proinsulin) mouse monoclonal antibody, clone D3E7 (5B6/6), Purified
Size:
200 ug
Conjugation:
Unconjugated
 

View other "Insulin or NP_000198" antibodies

Specifications
Product Data
Clone Name D3E7 (5B6/6)
Application ELISA, IHC
Recommended Dilution ELISA: This antibody is suitable for use as a Detection antibody with BM507 as the Capture antibody.
Immunohistochemistry on Frozen Sections (Ref.1).
Immunohistochemistry on Paraffin Sections: 1/100-1/300.
Reactivity Bovine, Human, Mouse, Porcine, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Recombinant Human Insulin.
Specificity This antibody recognizes both Insulin and Proinsulin, but does not react with free C-Peptide.
Buffer PBS
State: Purified
State: Liquid purified IgG fraction
Preservative: 0.09% Sodium Azide
Concentration lot specific
Purification Affinity Chromatography on Protein A
Conjugation Unconjugated
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Gene Name insulin
Database Link
Background Insulin is one of the major regulatory hormones of intermediate metabolism throughout the body. The biological actions of this hormone involve integration of carbohydrate, protein, and lipid metabolism. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Immunocytochemical investigations have localized insulin in the B cells of pancreatic islets of Langerhans. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of B cell origin such as insulinoma.
Synonyms INS
Reference Data
Protein Categories Cytokines, Diabetes, Growth Factors, Secreated Proteins
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein
Protein Pathways Insulin signaling pathway, Maturity onset diabetes of the young, mTOR signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation, Prostate cancer, Regulation of actin cytoskeleton, Regulation of autophagy, Type I diabetes mellitus, Type II diabetes mellitus
Product Manuals
FAQs
  • Antibody and Western Standard
SDS

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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