Insulin (INS) Mouse Monoclonal Antibody [Clone ID: E2E3]

Referencia BM504P

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Insulin (INS) Mouse Monoclonal Antibody [Clone ID: E2E3]

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SKU
BM504P
Insulin (INS) mouse monoclonal antibody, clone E2E3, Purified
 
Specifications
Product Data
Clone Name E2E3
Application ELISA, IHC, WB
Recommended Dilution ELISA.
Immunohistochemistry on formalin-fixed, paraffin-embedded tissues (1-2 µg/ml, incubate at RT for at least 1 hr.).
Western blot (1-5 µg/ml).
Reactivity Bovine, Human, Porcine
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Hybridoma produced by the fusion of splenocytes from mice immunized with full-length insulin protein and mouse myeloma cells.
Specificity This antibody detects Insulin.
Buffer PBS
State: Purified
State: Liquid purified Ig fraction
Preservative: 0.08% Sodium Azide
Concentration lot specific
Purification Affinity Chromatography on Protein A/G
Conjugation Unconjugated
Storage Upon receipt, store undiluted (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Gene Name insulin
Database Link
Background Insulin is one of the major regulatory hormones of intermediate metabolism throughout the body. The biological actions of this hormone involve integration of carbohydrate, protein, and lipid metabolism. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Immunocytochemical investigations have localized insulin in the B cells of pancreatic islets of Langerhans. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of B cell origin such as insulinoma.
Synonyms INS
Reference Data
Protein Categories Cytokines, Diabetes, Growth Factors, Secreated Proteins

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