INSIG1 Antibody - middle region - HRP
Referencia ARP40159_P050-HRP
embalaje : 100ul
Marca : Aviva Systems Biology
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INSIG1 Antibody - middle region : HRP (ARP40159_P050-HRP)
| Datasheets/Manuals | Printable datasheet for anti-INSIG1 (ARP40159_P050-HRP) antibody |
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| Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish |
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| Product Format | Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Conjugation | HRP: Horseradish Peroxidase |
| Application | IHC, WB |
| Reconstitution and Storage | All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
| Immunogen | The immunogen is a synthetic peptide directed towards the middle region of human INSIG1 |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 93% |
| Peptide Sequence | Synthetic peptide located within the following region: ITIAFLATLITQFLVYNGVYQYTSPDFLYIRSWLPCIFFSGGVTVGNIGR |
| Concentration | 0.5 mg/ml |
| Blocking Peptide | For anti-INSIG1 (ARP40159_P050-HRP) antibody is Catalog # AAP40159 (Previous Catalog # AAPP20903) |
| Reference | Roth,A., (2008) Mol. Pharmacol. 73 (4), 1282-1289 |
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| Gene Symbol | INSIG1 |
| Gene Full Name | Insulin induced gene 1 |
| Alias Symbols | CL6 |
| NCBI Gene Id | 3638 |
| Protein Name | Insulin induced gene 1 EMBL EAL23728.1 |
| Description of Target | Oxysterols regulate cholesterol homeostasis through the liver X receptor (LXR)- and sterol regulatory element-binding protein (SREBP)-mediated signaling pathways. This gene is an insulin-induced gene. INSIG1 is an endoplasmic reticulum (ER) membrane prote |
| Uniprot ID | A4D2M9 |
| Protein Accession # | NP_938150 |
| Nucleotide Accession # | NM_198336 |
| Protein Size (# AA) | 330 |
| Molecular Weight | 36kDa |
| Protein Interactions | UBC; HMGCR; FAF2; SCAP; ERLIN2; ERLIN1; VCP; AMFR; PGRMC1; POR; SREBF1; ELAVL1; RNF139; INSIG2; PSMC3; PSMA7; INSIG1; VAPA; VAPB; SREBF2; |
