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> IL-2 Protein, Mouse, Recombinant (His & Avi)

IL-2 Protein, Mouse, Recombinant (His & Avi)

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IL-2 Protein, Mouse, Recombinant (His & Avi)

(Synonyms: TCGF, T-cell growth factor, IL2, Aldesleukin) Copy Product Info

Synonyms: TCGF, T-cell growth factor, IL2, Aldesleukin

Catalog No. TMPK-00769 Copy Product Info
Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system. It is a 15,5 - 16 kDa protein that regulates the activities of white blood cells (leukocytes, often lymphocytes) that are responsible for immunity. IL-2 has essential roles in key functions of the immune system, tolerance and immunity, primarily via its direct effects on T cells. IL-2 Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 20.1 kDa and the accession number is P04351-1.
Other Forms of IL-2 Protein, Mouse, Recombinant (His & Avi):
IL-2 Protein, Human, Recombinant (His & Avi), Biotinylated
IL-2 Protein, Rat, Recombinant (His)
IL-2 Protein, Mouse, Recombinant (His & Avi), Biotinylated
IL-2 Protein, Human, Recombinant (E. coli)
IL-2 Superkine Protein, Human, Recombinant (L100F, R101D, L105V, I106V, I112F)
IL-2 Protein, Rhesus macaque, Recombinant (His & Myc & SUMO)
IL-2 Protein, Rabbit, Recombinant (His)
IL-2 Protein, Rat, Recombinant
IL-2 Protein, Canine, Recombinant (C147S)
IL-2 Protein, Mouse, Recombinant
IL-2 Protein, Human, Recombinant (His)
IL-2 Protein, Human, Recombinant
For research use only—not for human use. No sales to individuals. Use as intended only.
Select Batch
Purity:> 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC
Appearance:Lyophilized powder
Color:White
Contact us for more batch information

Product Introduction

Bioactivity
Bioactivity
1. Mouse IL-2 R alpha, His Tag immobilized on CM5 Chip can bind Mouse IL-2, His Tag with an affinity constant of 30.49 nM as determined in SPR assay. 2. Measured in a cell proliferation assay using CTLL‑2 mouse cytotoxic T cells. The ED50 for this effect is < 1 ng/mL.
Description
Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system. It is a 15,5 - 16 kDa protein that regulates the activities of white blood cells (leukocytes, often lymphocytes) that are responsible for immunity. IL-2 has essential roles in key functions of the immune system, tolerance and immunity, primarily via its direct effects on T cells. IL-2 Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 20.1 kDa and the accession number is P04351-1.
Species
Mouse
Expression System
HEK293 Cells
TagN-His-Avi
Accession NumberP04351-1
ConstructionAla21-Gln169
Protein Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
SynonymsTCGF, T-cell growth factor, IL2, Aldesleukin
Research Background
Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system. It is a 15,5 - 16 kDa protein that regulates the activities of white blood cells (leukocytes, often lymphocytes) that are responsible for immunity. IL-2 has essential roles in key functions of the immune system, tolerance and immunity, primarily via its direct effects on T cells.
Chemical Properties
Molecular Weight20.1 kDa (predicted). Due to glycosylation, the protein migrates to 27-30 kDa based on Tris-Bis PAGE result.
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

IL-2IL 2
Related Tags: IL-2 Protein, Mouse, Recombinant (His & Avi) chemical structure | IL-2 Protein, Mouse, Recombinant (His & Avi) molecular weight