IEX1 Polyclonal Antibody, PE-Cy5 Conjugated
Referencia bs-6840R-PE-Cy5
embalaje : 100uL
Marca : Bioss
Contact local distributor :
Teléfono : +1 850 650 7790
Applications
Predicted Reactivity
| Overview | |
| Catalog # | bs-6840R-PE-Cy5 |
| Product Name | IEX1 Polyclonal Antibody, PE-Cy5 Conjugated |
| Applications | WB |
| Predicted Reactivity | Human, Mouse, Rat, Dog, Cow, Sheep, Pig, Horse, Rabbit |
| Specifications | |
| Conjugation | PE-Cy5 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human IEX1/Differentiation dependent gene 2 protein |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 8870 |
| Swiss Prot | P46695 |
| Subcellular location | Cell membrane |
| Synonyms | DIF2; IEX1; PRG1; DIF-2; GLY96; IEX-1; IEX-1L; Radiation-inducible immediate-early gene IEX-1; Differentiation-dependent gene 2 protein; Protein DIF-2; Immediate early protein GLY96; Immediate early response 3 protein; PACAP-responsive gene 1 protein; Protein PRG1; IER3 |
| Background | May play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A-PPP2R5C holoenzyme. Acts also as an ERK downstream effector mediating survival. As a member of the NUPR1/RELB/IER3 survival pathway, may provide pancreatic ductal adenocarcinoma with remarkable resistance to cell stress, such as starvation or gemcitabine treatment. |
| Application Dilution | |
| WB | 1:300-5000 |