Human Lipoprotein lipase (LPL) activation kit by CRISPRa

Referencia GA102727

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Human Lipoprotein lipase (LPL) activation kit by CRISPRa

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SKU
GA102727
LPL CRISPRa kit - CRISPR gene activation of human lipoprotein lipase
 
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol LPL
Locus ID 4023
Components

GA102727G1, Lipoprotein lipase gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102727G2, Lipoprotein lipase gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102727G3, Lipoprotein lipase gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000237
UniProt ID P06858
Synonyms HDLCQ11; LIPD
Summary LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism. provided by RefSeq, Jul 2008
SKU Description Size
KN403766 LPL - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit

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