General Info
| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.55ng/mL |
| Detection Limit: | 1.56-100ng/mL |
| Short Description: | This gGT5 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 4.5 hrs |
Information
| Gene Symbol: | GGT5 |
| Gene ID: | 2687 |
| Uniprot ID: | GGT5_HUMAN |
| Sample Type: | serum, plasma, tissue homogenates or other biological fluids. |
Description
| Tissue Specificity | |
| Post Translational Modifications | Cleaved by autocatalysis into a large and a small subunit. Glycosylated. |
| Function | Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione-S-conjugate such as leukotriene C4. Does not cleaves gamma-glutamyl compounds such as gamma-glutamyl leucine. May also catalyze a transpeptidation reaction in addition to the hydrolysis reaction, transferring the gamma-glutamyl moiety to an acceptor amino acid to form a new gamma-glutamyl compound. Acts as a negative regulator of geranylgeranyl glutathione bioactivity by cleaving off its gamma-glutamyl group, playing a role in adaptive immune responses. |
| Protein Name | Glutathione Hydrolase 5 ProenzymeGamma-Glutamyl Transpeptidase-Related EnzymeGgt-RelGamma-Glutamyltransferase 5Ggt 5Gamma-Glutamyltransferase-Like Activity 1Gamma-Glutamyltranspeptidase 5Leukotriene-C4 Hydrolase Cleaved Into - Glutathione Hydrolase 5 Heavy Chain - Glutathione Hydrolase 5 Light Chain |
| Database Links | Reactome: R-HSA-174403Reactome: R-HSA-2142691Reactome: R-HSA-5423646Reactome: R-HSA-9664535Reactome: R-HSA-9753281 |
| Cellular Localisation | MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative ELISA Names | Glutathione Hydrolase 5 Proenzyme ELISA kitGamma-Glutamyl Transpeptidase-Related Enzyme ELISA kitGgt-Rel ELISA kitGamma-Glutamyltransferase 5 ELISA kitGgt 5 ELISA kitGamma-Glutamyltransferase-Like Activity 1 ELISA kitGamma-Glutamyltranspeptidase 5 ELISA kitLeukotriene-C4 Hydrolase Cleaved Into - Glutathione Hydrolase 5 Heavy Chain - Glutathione Hydrolase 5 Light Chain ELISA kitGGT5 ELISA kitGGTLA1 ELISA kit |
| output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance