HMGCS2 Antibody - N-terminal region - FITC

Referencia ARP41562_T100-FITC

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HMGCS2 Antibody - N-terminal region : FITC (ARP41562_T100-FITC)

Datasheets/ManualsPrintable datasheet for anti-HMGCS2 (ARP41562_T100-FITC) antibody
Product Info
Publications

Karimian Azari, E., Leitner, C., Jaggi, T., Langhans, W. & Mansouri, A. Possible role of intestinal fatty acid oxidation in the eating-inhibitory effect of the PPAR--alpha agonist Wy-14643 in high-fat diet fed rats. PLoS One 8, e74869 (2013). Chip-Seq, ChIP, Dog, Horse, Rabbit, Rat, Guinea pig, Human, Mouse, Goat, Bovine 24069361

Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer.
ClonalityPolyclonal
HostRabbit
ConjugationFITC: Fluorescein Isothiocyanate
ApplicationWB
Reconstitution and StorageAll conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human HMGCS2
Predicted Homology Based on Immunogen SequenceCow: 93%; Dog: 100%; Goat: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Peptide SequenceSynthetic peptide located within the following region: PKDVGILALEVYFPAQYVDQTDLEKYNNVEAGKYTVGLGQTRMGFCSVQE
Concentration0.5 mg/ml
Blocking PeptideFor anti-HMGCS2 (ARP41562_T100-FITC) antibody is Catalog # AAP41562 (Previous Catalog # AAPP24247)
ReferenceBouchard,L., (2001) Pediatr. Res. 49 (3), 326-331
Gene SymbolHMGCS2
Gene Full Name3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
NCBI Gene Id3158
Protein NameHydroxymethylglutaryl-CoA synthase, mitochondrial
Description of TargetHMGCS2 condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
Uniprot IDP54868
Protein Accession #NP_005509
Nucleotide Accession #NM_005518
Protein Size (# AA)508
Molecular Weight56kDa
Protein InteractionsUBC; APP; YWHAQ;