• Specifications

    Product Description

    PE conjugated mouse monoclonal antibody raised against a partial recombinant GLUL.
    This product is belong to Cell Culture Grade Antibody (CX Grade).Cell Culture Grade Antibody,Cell Culture Grade Antibodies,Cell Culture Grade,CX Grade,CXGrade,small size,trial size,MAB,monoclonal Ab,monoclonal antibody

    Immunogen

    GLUL (NP_002056.2, 274 a.a. ~ 373 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    Sequence

    IEKLSKRHQYHIRAYDPKGGLDNARRLTGFHETSNINDFSAGVANRSASIRIPRTVGQEKKGYFEDRRPSANCDPFSVTEALIRTCLLNETGDEPFQYKN

    Host

    Mouse

    Reactivity

    Human

    Interspecies Antigen Sequence

    Mouse (94); Rat (94)

    Conjugation

    PE

    Preparation Method

    Cell Culture Production

    Isotype

    IgG1 Kappa

    Quality Control Testing

    Antibody Reactive Against Recombinant Protein.

    Storage Buffer

    In 1x PBS, pH 7.4

    Storage Instruction

    Store at 4°C.

  • Applications

    Flow Cytometry

    Immunofluorescence

    Western Blot

  • Gene Info — GLUL

    Entrez GeneID

    2752

    GeneBank Accession#

    NM_002065.4

    Protein Accession#

    NP_002056.2

    Gene Name

    GLUL

    Gene Alias

    GLNS, GS, PIG43, PIG59

    Gene Description

    glutamate-ammonia ligase (glutamine synthetase)

    Omim ID

    138290 610015

    Gene Ontology

    Hyperlink

    Gene Summary

    Glutamine is a main source of energy and is involved in cell proliferation, inhibition of apoptosis, and cell signaling (Haberle et al., 2005 [PubMed 16267323]). Fetal glutamine requirements are very high and depend largely on active glutamine synthesis and the release of glutamine into the fetal circulation by the placenta. Glutamine synthetase (EC 6.3.1.2), also called glutamate-ammonia ligase (GLUL), is expressed throughout the body and plays an important role in controlling body pH and in removing ammonia from the circulation. The enzyme clears L-glutamate, the major neurotransmitter in the central nervous system, from neuronal synapses (see references in Clancy et al., 1996 [PubMed 8975719]).[supplied by OMIM

    Other Designations

    OTTHUMP00000035524|OTTHUMP00000035525|cell proliferation-inducing protein 59|glutamate-ammonia ligase (glutamine synthase)|glutamine synthetase|proliferation-inducing protein 43

  • Interactomes
  • Pathways
  • Diseases