- Specifications
Product Description
PE conjugated mouse monoclonal antibody raised against a partial recombinant GBA.
This product is belong to Cell Culture Grade Antibody (CX Grade).Immunogen
GBA (NP_000148.2, 146 a.a. ~ 235 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
SYFSEEGIGYNIIRVPMASCDFSIRTYTYADTPDDFQLHNFSLPEEDTKLKIPLIHRALQLAQRPVSLLASPWTSPTWLKTNGAVNGKGS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (84); Rat (88)
Conjugation
PE
Preparation Method
Cell Culture Production
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at 4°C.
- Applications
Flow Cytometry
Immunofluorescence
Western Blot
- Gene Info — GBA
Entrez GeneID
2629GeneBank Accession#
NM_000157.1Protein Accession#
NP_000148.2Gene Name
GBA
Gene Alias
GBA1, GCB, GLUC
Gene Description
glucosidase, beta; acid (includes glucosylceramidase)
Gene Ontology
HyperlinkGene Summary
This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq
Other Designations
D-glucosyl-N-acylsphingosine glucohydrolase|OTTHUMP00000033992|OTTHUMP00000033993|glucocerebrosidase|glucocerebrosidase (alt.)|lysosomal glucocerebrosidase
- Interactomes
- Pathways
- Diseases
GBA monoclonal antibody (MP01J), clone 2E2 (PE)
Referencia H00002629-MP01J-50ug
embalaje : 50ug
Marca : Abnova
Contact local distributor :
Teléfono : +1 850 650 7790