FXN Capture Antibody
Referencia OAOA21830
embalaje : 100µg
Marca : Aviva Systems Biology
Contact local distributor :
Teléfono : +1 850 650 7790
FXN Capture Antibody (OAOA21830)
| Datasheets/Manuals | Printable datasheet for FXN Capture Antibody (OAOA21830) |
|---|
| Predicted Species Reactivity | Human |
|---|---|
| Product Format | Stored in PBS (pH 7.4) containing 0.05% sodium azide and up to 5% trehalose |
| Clonality | Monoclonal |
| Clone | OTI4D7 |
| Isotype | IgG1 |
| Host | Mouse |
| Application | MlpxA |
| Reconstitution and Storage | -20°C |
| Immunogen | Full length human recombinant protein of human FXN (NM_000144) produced in HEK293T cell. |
| Concentration | 0.5 mg/ml |
| Dilution | 1:100 - 1:1000 |
| Description | FXN mouse monoclonal capture antibody, validated for Luminex assays |
| Gene Symbol | FXN |
|---|---|
| Gene Full Name | frataxin |
| Alias Symbols | CyaY, FA, FARR, frataxin, mitochondrial, FRDA, Friedreich ataxia protein, X25. |
| NCBI Gene Id | 2395 |
| Protein Name | Frataxin, mitochondrial|Homo sapiens frataxin (FXN), transcript variant 1, mRNA |
| Description of Target | Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe(2+) to Fe(3+); the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization; however, the physiological relevance is unsure as reports are conflicting and the function has only been shown using heterologous overexpression systems. Modulates the RNA-binding activity of ACO1. |
| Uniprot ID | Q16595 |
| Protein Accession # | NP_000135 |
| Nucleotide Accession # | https://www.ncbi.nlm.nih.gov/nuccore/NM_000144 |
