Eucalyptol [470-82-6]
Referencia M10345-10mL
embalaje : 10mL
Marca : AbMole Bioscience
Contact local distributor :
Teléfono : +1 850 650 7790
All AbMole products are for research use only, cannot be used for human consumption.
1,8-Cineole
Quality Control & Documentation
Biological Activity
Eucalyptol is an inhibitor of 5-HT3 receptor, potassium channel, with anti-inflammatory and antioxidant activities. In addition, eucalyptol shows neuroprotective effects in ischemic stroke models, anti-inflammatory effects in neurodegenerative diseases such as Alzheimer's disease.
Chemical Information
| Molecular Weight | 154.25 |
| Formula | C10H18O |
| CAS Number | 470-82-6 |
| Solubility (25°C) | DMSO ≥ 60 mg/mL |
| Storage | 2-8°C, dry, sealed |
References
[1] Germana Freire Rocha Caldas, et al. Food Chem Toxicol. Repeated-doses and reproductive toxicity studies of the monoterpene 1,8-cineole (eucalyptol) in Wistar rats
[2] Gavin E Jarvis, et al. J Pharmacol Exp Ther. Noncompetitive Inhibition of 5-HT3 Receptors by Citral, Linalool, and Eucalyptol Revealed by Nonlinear Mixed-Effects Modeling
[3] Zahra Zeraatpisheh, et al. Eur J Pharmacol. Eucalyptol induces hyperexcitability and epileptiform activity in snail neurons by inhibiting potassium channels
[4] Andleeb Khan, et al. Neurochem Res. 1,8-cineole (eucalyptol) mitigates inflammation in amyloid Beta toxicated PC12 cells: relevance to Alzheimer's disease