EGTA [67-42-5]

Referencia NB-64-28845-2g

embalaje : 2g

Marca : Neo Biotech

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Teléfono : +1 850 650 7790

EGTA (Synonyms: Ethylenebis(oxyethylenenitrilo)tetraacet)

Catalog No. T4585 Copy Product Info
Purity: 99.61%
Ethylenebis(oxyethylenenitrilo)tetraacet is a diether that is ethylene glycol in which the hydrogens of the hydroxy groups have been replaced by 2-[bis(carboxymethyl)amino]ethyl group respectively.

EGTA

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Synonyms Ethylenebis(oxyethylenenitrilo)tetraacet

Ethylenebis(oxyethylenenitrilo)tetraacet is a diether that is ethylene glycol in which the hydrogens of the hydroxy groups have been replaced by 2-[bis(carboxymethyl)amino]ethyl group respectively.

EGTA
Cas No. 67-42-5
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Purity:99.61%
Appearance:Solid
Color:White
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Product Introduction

EGTA AI Summary
EGTA exhibits multi-faceted biological activities. It significantly inhibits the invasion of Plasmodium falciparum FCB2 merozoites into human erythrocytes, showing an inhibition rate of 83.0% at a concentration of 50 mM and 90.0% at 1.9 mg/mL after 18 hours. Additionally, it demonstrates a substantial inhibition of aph8 phosphorylation in Streptomyces coelicolor cell lysate, achieving a 94.0% inhibition as assessed by [32Pi] incorporation. Moreover, compound 405836 is involved in inhibiting various enzymes and biological processes, including APE1, fructose-1,6-bisphosphate aldolase, Bloom's syndrome helicase BLM, HADH2, and histone lysine methyltransferase G9a. It also modulates PMP22 expression/activity, acts as an allosteric agonist for the human D1 dopamine receptor, and inhibits cell entry of Lassa and Marburg viruses. Additionally, it enhances Arylsulfatase A and activates the ryanodine receptor in Spodoptera litura muscle membrane, inducing a Ca2+ pump activity at 0.8 mM after 30 minutes..
Note: Summary generated by AI. Data source: ChEMBL
Bioactivity
Description
Ethylenebis(oxyethylenenitrilo)tetraacet is a diether that is ethylene glycol in which the hydrogens of the hydroxy groups have been replaced by 2-[bis(carboxymethyl)amino]ethyl group respectively.
SynonymsEthylenebis(oxyethylenenitrilo)tetraacet
Chemical Properties
Molecular Weight380.35
FormulaC14H24N2O10
Cas No.67-42-5
SmilesOC(=O)CN(CCOCCOCCN(CC(O)=O)CC(O)=O)CC(O)=O
Relative Density.1.433 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
0.1 M NaOH: 25 mg/mL (65.73 mM), Sonication is recommended.
DMSO: Insoluble
H2O: < 1 mg/mL (insoluble)
Solution Preparation Table
0.1 M NaOH
1mg5mg10mg50mg
1 mM2.6292 mL13.1458 mL26.2916 mL131.4579 mL
5 mM0.5258 mL2.6292 mL5.2583 mL26.2916 mL
10 mM0.2629 mL1.3146 mL2.6292 mL13.1458 mL
20 mM0.1315 mL0.6573 mL1.3146 mL6.5729 mL
50 mM0.0526 mL0.2629 mL0.5258 mL2.6292 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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