Dicamba [1918-00-9]

Dicamba is a herbicide. Dicamba is currently used in agriculture and gardening to control the growth of different unwanted vegetable species, mainly in cereal grain crops, but also on sugar cane and soybeans, among others. Dicambais induces significant DNA damage. Dicambais induces genotoxicity and cytotoxicity.

Dicamba (1229 mg/L; 48 h) increases frequency of MNs in in peripheral blood erythrocytes of C. decemmaculatus^[1].
Dicamba (50.0-500.0 μg/mL; 90 min) induces significant DNA damage in Chinese hamster ovary (CHO) cells, with an increased proportion of damaged cells^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

• [1]. Ruiz de Arcaute C, et al. Evaluation of the genotoxicity of a herbicide formulation containing 3,6-dichloro-2-metoxybenzoic acid (dicamba) in circulating blood cells of the tropical fish Cnesterodon decemmaculatus. Mutat Res Genet Toxicol Environ Mutagen. 2014;773:1-8.  [Content Brief]

  [2]. González NV, et al. The chlorophenoxy herbicide dicamba and its commercial formulation banvel induce genotoxicity and cytotoxicity in Chinese hamster ovary (CHO) cells. Mutat Res. 2007;634(1-2):60-68.  [Content Brief]