CREB1 Antibody - middle region - HRP
Referencia ARP39811_P050-HRP
embalaje : 100ul
Marca : Aviva Systems Biology
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CREB1 Antibody - middle region : HRP (ARP39811_P050-HRP)
| Datasheets/Manuals | Printable datasheet for anti-CREB1 (ARP39811_P050-HRP) antibody |
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| Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish |
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| Product Format | Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Conjugation | HRP: Horseradish Peroxidase |
| Application | WB |
| Reconstitution and Storage | All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
| Immunogen | The immunogen is a synthetic peptide directed towards the middle region of human CREB1 |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 86% |
| Peptide Sequence | Synthetic peptide located within the following region: TYQIRTAPTSTIAPGVVMASSPALPTQPAEEAARKREVRLMKNREAAREC |
| Concentration | 0.5 mg/ml |
| Blocking Peptide | For anti-CREB1 (ARP39811_P050-HRP) antibody is Catalog # AAP39811 (Previous Catalog # AAPP21825) |
| Sample Type Confirmation | CREB1 is strongly supported by BioGPS gene expression data to be expressed in HT1080 There is BioGPS gene expression data showing that CREB1 is expressed in HEK293 |
| Reference | Mamdani,F., Am. J. Med. Genet. B Neuropsychiatr. Genet. 147B (4), 500-504 |
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| Gene Symbol | CREB1 |
| Gene Full Name | CAMP responsive element binding protein 1 |
| Alias Symbols | CREB, CREB-1 |
| NCBI Gene Id | 1385 |
| Protein Name | Cyclic AMP-responsive element-binding protein 1 |
| Description of Target | CREB1 is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms. |
| Uniprot ID | P16220 |
| Protein Accession # | NP_604391 |
| Nucleotide Accession # | NM_134442 |
| Protein Size (# AA) | 341 |
| Molecular Weight | 37kDa |
| Protein Interactions | UBC; NCOR1; CREM; CREBBP; RPS6KA1; NR5A2; EP300; DEAF1; TP53; CREB1; PRKG1; YAP1; MAPK14; MEIS1; DAXX; TSSK4; AKT1; ATR; SIRT1; SRA1; DR1; ATF7; GSK3B; GSK3A; ATXN3; DNMT3B; RPS6KA5; YY1; RGS13; JUN; HDAC2; HDAC1; CCDC6; PPP1CA; SUMO1; TAF4; POU2F1; MYOD1 |
