CD40 (AP)
Referencia MBS6247621-5x0,1mL
embalaje : 5x0.1mL
Marca : MyBiosource
Contact local distributor :
Teléfono : +1 850 650 7790
Bovine peripheral blood lymphocytes stained with 214686 followed by Goat anti Mouse IgG: FITC.
CD40 Antibody – Mouse Monoclonal
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6247621MBS6247621 is an antibody targeting CD40. Also known as CD40 (AP). Reactive in Bovine, Sheep. Host: Mouse. More details
Product Overview
Online Datasheet in PDFProduct Name
CD40, Monoclonal Antibody
Full Product Name
CD40 (AP)
Product Gene Name
anti-CD40 antibody
Clonality
Monoclonal
Isotype
IgG1
Clone Number
IL-A156
Host
Mouse
Species Reactivity
Bovine, Sheep
Form/Format
Supplied as a liquid in PBS, pH 7.2. Labeled with Alkaline Phosphatase.
Purity/Purification
Purified by protein G affinity chromatography from tissue culture supernatant.
Specificity
Recognizes bovine CD40. Species Crossreactivity: sheep
Preparation and Storage
Store at 4 degree C. Do Not Freeze.
Product References and Citations for anti-CD40 antibody
1. Langelaar, M.F. et al. (2005) Mycobacterium avium ssp. paratuberculosis recombinant heat shock protein 70interaction with different bovine antigen-presenting cells. Scand J Immunol. 61: 242-50. 2. Epardaud, M. et al. (2004) Enrichment for a CD26hi SIRP subset in lymph dendritic cells from the upper aero-digestive tract. J. Leukoc. Biol. 76: 553-561. 3. Glew, E.J. et al. (2003) Differential effects of bovine viral diarrhoea virus on monocytes and dendritic cells. J. Gen. Virol. 84: 1771-1780. 4. Norimatsu, M. et al. (2003) Differential response of bovine monocyte-derived macrophages and dendritic cells to infection with Salmonella typhimurium in a low-dose model in vitro. Immunology 108: 55- 61. 5. Haas, K.M. et al. (2001) Enhancing effects of anti-CD40 treatment on the immune response of SCID-bovine mice to Trypanosoma congolense infection. J Leukoc Biol. 70: 931-40.
Other Notes
Small volumes of anti-CD40 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for CD40. It may not necessarily be applicable to this product.
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
tumor necrosis factor receptor superfamily member 5
NCBI Official Synonym Full Names
CD40 molecule, TNF receptor superfamily member 5<
NCBI Official Symbol
CD40
NCBI Official Synonym Symbols
TNFRSF5
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 5
UniProt Synonym Protein Names
B-cell surface antigen CD40; CD40L receptor; CD_antigen: CD40
Protein Family
Tumor necrosis factor receptor superfamily
UniProt Gene Name
CD40
UniProt Synonym Gene Names
TNFRSF5
UniProt Entry Name
TNR5_BOVIN
NCBI Protein Information
tumor necrosis factor receptor superfamily member 5; B-cell surface antigen CD40; CD40L receptor; tumor necrosis factor receptor superfamily, member 5
UniProt Comments for CD40
Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Pathways associated with anti-CD40 antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Adaptive Immune System Pathway antibodies | Adaptive Immune System Pathway Diagram |
| Allograft Rejection Pathway antibodies | Allograft Rejection Pathway Diagram |
| Allograft Rejection Pathway antibodies | Allograft Rejection Pathway Diagram |
| Asthma Pathway antibodies | Asthma Pathway Diagram |
| Asthma Pathway antibodies | Asthma Pathway Diagram |
| Autoimmune Thyroid Disease Pathway antibodies | Autoimmune Thyroid Disease Pathway Diagram |
| Autoimmune Thyroid Disease Pathway antibodies | Autoimmune Thyroid Disease Pathway Diagram |
| Cell Adhesion Molecules (CAMs) Pathway antibodies | Cell Adhesion Molecules (CAMs) Pathway Diagram |
| Cell Adhesion Molecules (CAMs) Pathway antibodies | Cell Adhesion Molecules (CAMs) Pathway Diagram |
| Cytokine-cytokine Receptor Interaction Pathway antibodies | Cytokine-cytokine Receptor Interaction Pathway Diagram |
Diseases associated with anti-CD40 antibody
| Disease Name | Pubmed Publications |
|---|---|
| Necrosis Antibodies | >2264 publications with CD40 and Necrosis |
| Inflammation Antibodies | >1620 publications with CD40 and Inflammation |
| Cardiovascular Diseases Antibodies | >1089 publications with CD40 and Cardiovascular Diseases |
| Disease Models, Animal Antibodies | >735 publications with CD40 and Disease Models, Animal |
| Atherosclerosis Antibodies | >486 publications with CD40 and Atherosclerosis |
| Heart Diseases Antibodies | >455 publications with CD40 and Heart Diseases |
| Neoplasms, Experimental Antibodies | >429 publications with CD40 and Neoplasms, Experimental |
| Arthritis, Rheumatoid Antibodies | >260 publications with CD40 and Arthritis, Rheumatoid |
| Liver Diseases Antibodies | >201 publications with CD40 and Liver Diseases |
| Kidney Diseases Antibodies | >195 publications with CD40 and Kidney Diseases |
Organs/Tissues associated with anti-CD40 antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Lung Antibodies | >436 publications with CD40 and Lung |
| Kidney Antibodies | >371 publications with CD40 and Kidney |
| Brain Antibodies | >316 publications with CD40 and Brain |
| Intestine Antibodies | >166 publications with CD40 and Intestine |
| Pancreas Antibodies | >101 publications with CD40 and Pancreas |
| Cartilage Antibodies | >27 publications with CD40 and Cartilage |
| Mammary Gland Antibodies | >7 publications with CD40 and Mammary Gland |
| Lymphoreticular Antibodies | >6 publications with CD40 and Lymphoreticular |
| Extraembryonic Tissue Antibodies | >3 publications with CD40 and Extraembryonic Tissue |
| Uncharacterized Tissue Antibodies | >2 publications with CD40 and Uncharacterized Tissue |