CD3E Antibody
Referencia OABF00425
embalaje : 100ul
Marca : Aviva Systems Biology
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Teléfono : +1 850 650 7790
HNRNPK Recombinant Antibody [3G7] (OACA12142)
| Datasheets/Manuals | Printable datasheet for HNRNPK Recombinant Antibody [3G7] (OACA12142) |
|---|
| Predicted Species Reactivity | Human |
|---|---|
| Product Format | Liquid |
| Clonality | Recombinant Monoclonal |
| Conjugation | Unconjugated |
| Application | Enzyme-linked immunosorbent assay, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western blot |
| Reconstitution and Storage | -20°C or -80°C |
| Immunogen | A synthesized peptide derived from human HNRNPK |
| Purification | Affinity Purified |
| Gene Symbol | HNRNPK |
|---|---|
| Gene Full Name | heterogeneous nuclear ribonucleoprotein K |
| Alias Symbols | AUKS;CSBP;dC-stretch binding protein;heterogeneous nuclear ribonucleoprotein K;HNRPK;transformation upregulated nuclear protein;Transformation up-regulated nuclear protein;TUNP. |
| NCBI Gene Id | 3190 |
| Protein Name | Heterogeneous nuclear ribonucleoprotein K |
| Description of Target | One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction (By similarity). As far as transcription repression is concerned, acts by interacting with long intergenic RNA p21 (lincRNA-p21), a non-coding RNA induced by p53/TP53. This interaction is necessary for the induction of apoptosis, but not cell cycle arrest. |
| Uniprot ID | P61978 |