CD2 Antibody
Referencia OAEE00711
embalaje : 100tests(T100)
Marca : Aviva Systems Biology
Contact local distributor :
Teléfono : +1 850 650 7790
| Datasheets/Manuals | Printable datasheet for CD2 Antibody |
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| Predicted Species Reactivity | Human |
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| Product Format | Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
| Clonality | Monoclonal |
| Clone | LT2 |
| Isotype | IgG2b |
| Host | Mouse |
| Conjugation | R-PE |
| Application | FC |
| Reconstitution and Storage | 2°C to 8°C |
| Immunogen | Normal human blood lymphocytes. |
| Purification | Purified by size-exclusion chromatography |
| Concentration | 20 ul / test |
| Specificity | The antibody LT2 reacts with CD2, a 50 kDa glycoprotein present on the human peripheral blood T lymphocytes and NK cells; also expressed by all thymocytes. HLDA VI; WS Code T 6T-008 |
| Formulation | PE |
| Storage Buffer | The reagent is provided in phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent. |
| Reference | Lin CW, Liu TY, Chen SU, Wang KT, Medeiros LJ, Hsu SM: CD94 1A transcripts characterize lymphoblastic lymphoma/leukemia of immaturenatural killer cell origin with distinct clinical features. Blood. 2005 Nov 15;106(10):3567-74. Gannon GA, Rhind SG, Suzui M, Zamecnik J, Sabiston BH, Shek PN, Shephard RJ: beta-Endorphin and natural killer cell cytolytic activity during prolonged exercise. Is there a connection? Am J Physiol. 1998 Dec;275(6 Pt 2):R1725-34., Filatov AV, Bachurin PS, Markova NA, Surnakova NE: [A panel of monoclonal antibodies against human lymphocyte antigens] Eksp Onkol. 1989;11(2):28-32. Leukocyte Typing VI., Kishimoto T. et al. (Eds.), Garland Publishing Inc. (1997). Pawlowski NN, Struck D, Grollich K, Kuhl AA, Zeitz M, Liesenfeld O, Hoffmann JC.: CD2 deficiency partially prevents small bowel inflammation and improves parasite control in murine Toxoplasma gondii infection. World J Gastroenterol. 2007 Aug 21;13(31):4207-13. Zhu DM, Dustin ML, Cairo CW, Thatte HS, Golan DE.:Mechanisms of Cellular Avidity Regulation in CD2-CD58-Mediated T Cell Adhesion. ACS Chem Biol. 2006 Nov 21;1(10):649-58. Dustin ML: Adhesive bond dynamics in contacts between T lymphocytes and glass-supportedplanar bilayers reconstituted with the immunoglobulin-related adhesion moleculeCD58. J Biol Chem. 1997 Jun 20;272(25):15782-8. |
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| Gene Symbol | CD2 |
| Gene Full Name | CD2 molecule |
| Alias Symbols | CD2 antigen (p50), sheep red blood cell receptor, erythrocyte receptor, LFA-2, LFA-3 receptor, lymphocyte-function antigen-2, rosette receptor, SRBC, T-cell surface antigen CD2, T-cell surface antigen T11/Leu-5, T11. |
| NCBI Gene Id | 914 |
| Protein Name | T-cell surface antigen CD2 |
| Description of Target | CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. |
| Uniprot ID | P06729 |
| Protein Accession # | NP_001758.2 |
| Nucleotide Accession # | NM_001767.3 |
