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> c-Myc Protein, Human, Recombinant (Avi & His & MBP), Biotinylated

c-Myc Protein, Human, Recombinant (Avi & His & MBP), Biotinylated

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c-Myc Protein, Human, Recombinant (Avi & His & MBP), Biotinylated

(Synonyms: Transcription factor p64, Proto-oncogene c-Myc, Myc proto-oncogene protein, MYC, Class E basic helix-loop-helix protein 39 (bHLHe39), BHLHE39) Copy Product Info

Synonyms: Transcription factor p64, Proto-oncogene c-Myc, Myc proto-oncogene protein, MYC, Class E basic helix-loop-helix protein 39 (bHLHe39), BHLHE39

Catalog No. TMPH-01721 Copy Product Info
Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release. c-Myc Protein, Human, Recombinant (Avi & His & MBP), Biotinylated is expressed in E. coli expression system with N-MBP and C-6xHis-Avi tag. The predicted molecular weight is 96.6 kDa and the accession number is P01106.
Other Forms of c-Myc Protein, Human, Recombinant (Avi & His & MBP), Biotinylated:
c-Myc Protein, Human, Recombinant (His)
c-Myc Protein, Mouse, Recombinant (GST)
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:85%
Appearance:Lyophilized powder
Color:White
Contact us for more batch information

Product Introduction

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release. c-Myc Protein, Human, Recombinant (Avi & His & MBP), Biotinylated is expressed in E. coli expression system with N-MBP and C-6xHis-Avi tag. The predicted molecular weight is 96.6 kDa and the accession number is P01106.
Species
Human
Expression System
E. coli
TagN-MBP, C-6xHis-Avi
Accession NumberP01106
Amino AcidMPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQQQSELQPPAPSEDIWKKFELLPTPPLSPSRRSGLCSPSYVAVTPFSLRGDNDGGGGSFSTADQLEMVTELLGGDMVNQSFICDPDDETFIKNIIIQDCMWSGFSAAAKLVSEKLASYQAARKDSGSPNPARGHSVCSTSSLYLQDLSAAASECIDPSVVFPYPLNDSSSPKSCASQDSSAFSPSSDSLLSSTESSPQGSPEPLVLHEETPPTTSSDSEEEQEDEEEIDVVSVEKRQAPGKRSESGSPSAGGHSKPPHSPLVLKRCHVSTHQHNYAAPPSTRKDYPAAKRVKLDSVRVLRQISNNRKCTSPRSSDTEENVKRRTHNVLERQRRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYILSVQAEEQKLISEEDLLRKRREQLKHKLEQLRNSCA
Construction1-439 aa
Protein Purity
> 85% as determined by SDS-PAGE.
c-Myc Protein, Human, Recombinant (Avi & His & MBP), Biotinylated
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
ReconstitutionReconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
SynonymsTranscription factor p64, Proto-oncogene c-Myc, Myc proto-oncogene protein, MYC, Class E basic helix-loop-helix protein 39 (bHLHe39), BHLHE39
Research Background
Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release.
Chemical Properties
Molecular Weight96.6 kDa (predicted)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

bHLHe39bHLHe 39
Related Tags: c-Myc Protein, Human, Recombinant (Avi & His & MBP), Biotinylated chemical structure | c-Myc Protein, Human, Recombinant (Avi & His & MBP), Biotinylated molecular weight