APC Anti-Human CD197/CCR7 Antibody[G043H7]
Referencia E-AB-F1159E-100
embalaje : 100Tests
Marca : Elabscience
Contact local distributor :
Teléfono : +1 850 650 7790
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Cell Markers ![APC Anti-Human CD197/CCR7 Antibody[G043H7] - 1](/proxy_img/Ly9maWxlLmVsYWJzY2llbmNlLmNvbS9hc3NldHMvaW1hZ2VzL2xvYWRpbmcucG5n.png)
For research use only.
Conjugation: APC
APC Elab Fluor®488 Elab Fluor®647 Elab Fluor®700 Elab Fluor®Red 780 Elab Fluor®Violet 450 Elab Fluor®Violet 610 FITC PE PE/Cyanine 5 PE/Cyanine 5.5 PE/Cyanine 7 PerCP/Cyanine 5.5 Unconjugated Show More
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| Alternate Names | EBI1EVI1, CCR-7, CDw197, CMKBR7 |
| Clone | |
| Leadtime | Order now, ship in 3 days |
| Background | CCR7, also known as CD197, is a chemokine receptor that binds CCL19 and CCL21. CCR7 and its ligands link innate and adaptive immunity by affecting interactions between T cells and dendritic cells and their downstream effect. Naïve T cells enter the lymph node through high endothelial venules, which express CCL21. Dendritic cells and macrophages enter the lymph node through afferent lymphatics. The encounter of T cells and dendritic cells in the T cell zone is CCR7-dependent. In addition, during immunological surveillance, B cells recirculate between B-cell-rich compartments (follicles or B cell zones) in secondary lymphoid organs, surveying for antigen. After antigen binding, B cells move to the boundary of B and T zones to interact with T-helper cells; this B cell migration is directed by CCR7 and its ligands. CCR7-positive cancer cell expression has been associated with lymph node metastasis. |
| Abbre | CD197/CCR7 |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype | Mouse IgG2a, κ |
| Isotype Control | APC Mouse IgG2a, κ Isotype Control[C1.18.4] |
| Applications | FCM |
| Research Areas | Immunology |
| Cellular Localization | Membrane |
| Form | Liquid |
| Concentration | 5 μL/Test |
| Conjugation | APC |
| Conjugation Information | APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter). |
| Spectrum | |
| Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Storage | This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze. |
| Expiration Date | 24 months |
| Shipping | Ice bag |
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