General Information
| Short Description | Rabbit polyclonal antibody anti-TICRR is suitable for use in ELISA and Western Blot research applications. |
| Applications | ELISA/WB |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | FITC |
| Concentration | 0.55-0.75 µg/µl |
| Purification | Affinity Purified |
| Dilution Range | WB: 1:500DB: 1:10, 000ELISA: 1:10, 000 |
| Formulation | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | |
| Gene ID | |
| Uniprot ID | |
| Immunogen | Synthetic peptide corresponding to unique amino acid sequence on human Treslin protein. |
Additional Info
| Function | Regulator of DNA replication and S/M and G2/M checkpoints. Regulates the triggering of DNA replication initiation via its interaction with TOPBP1 by participating in CDK2-mediated loading of CDC45L onto replication origins. Required for the transition from pre-replication complex (pre-RC) to pre-initiation complex (pre-IC). Required to prevent mitotic entry after treatment with ionizing radiation. |
| Protein Name | TreslinTopbp1-Interacting Checkpoint And Replication RegulatorTopbp1-Interacting - Replication-Stimulating Protein |
| Cellular Localisation | NucleusAssociates With Chromatin |
| Alternative Antibody Names | Anti-Treslin antibodyAnti-Topbp1-Interacting Checkpoint And Replication Regulator antibodyAnti-Topbp1-Interacting - Replication-Stimulating Protein antibodyAnti-TICRR antibodyAnti-C15orf42 antibody |
Information sourced from Uniprot.org