Anti-Thyroid hormone receptor alpha Polyclonal Antibody
Referencia NB-64-163449-50uL
embalaje : 50uL
Marca : Neo Biotech
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Teléfono : +1 850 650 7790
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Anti-Thyroid hormone receptor alpha Polyclonal Antibody
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Catalog No. TMAB-13531 Copy Product Info
Anti-Thyroid hormone receptor alpha Polyclonal Antibody is a Rabbit antibody targeting Thyroid hormone receptor alpha. Anti-Thyroid hormone receptor alpha Polyclonal Antibody can be used in WB,FCM.
For research use only—not for human use. No sales to individuals. Use as intended only.
Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Thyroid hormone receptor alpha Polyclonal Antibody is a Rabbit antibody targeting Thyroid hormone receptor alpha. Anti-Thyroid hormone receptor alpha Polyclonal Antibody can be used in WB,FCM. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Chicken,Pig,Horse,Rabbit,Sheep,GuineaPig) |
| Verified Activity | 1. Sample: Liver (Mouse) Lysate at 40 μg Primary: Anti-Thyroid hormone receptor alpha (TMAB-13531) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 55 kD Observed band size: 55 kD 2. Blank control (blue): Hela (fixed with 2% paraformaldehyde (10 min), then permeabilized with 90% ice-cold methanol for 30 min on ice). Primary Antibody: Rabbit Anti-Thyroid hormone receptor alpha antibody (TMAB-13531), Dilution: 1 μg in 100 μL 1X PBS containing 0.5% BSA; Isotype Control Antibody: Rabbit IgG (orange), used under the same conditions); Secondary Antibody: Goat anti-rabbit IgG-PE (white blue), Dilution: 1: 200 in 1 X PBS containing 0.5% BSA. 3. Sample: Liver (Rat) Lysate at 40 μg Primary: Anti-Thyroid hormone receptor alpha (TMAB-13531) at 1/500 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 55 kD Observed band size: 55 kD |
| Application | WB FCM |
| Recommended Dose | WB: 1:500-2000; FCM: 1μg/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Tissue Specificity | After the mid-blastula transition (MBT), expressed throughout the deep cells, which give rise to the embryo proper. In adults, isoform 2 shows highest expression in the eye and liver. Expressed in adult gonads. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]. |
| Immunogen | KLH conjugated synthetic peptide: human Thyroid hormone receptor alpha |
| Antigen Species | Human |
| Gene Name | THRA |
| Gene ID | 7067 |
| Protein Name | Thyroid hormone receptor alpha |
| Uniprot ID | P10827 |
| Function | Nuclear hormone receptor. High affinity receptor for triiodothyronine. |
| Molecular Weight | Theoretical: 55 kDa. Actual: 55 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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