General Information
| Short Description | Rabbit polyclonal anti-Pogo transposable element with ZNF domain for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | |
| Gene ID | |
| Uniprot ID | |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | POGZ Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Plays a role in mitotic cell cycle progression and is involved in kinetochore assembly and mitotic sister chromatid cohesion. Probably through its association with CBX5 plays a role in mitotic chromosome segregation by regulating aurora kinase B/AURKB activation and AURKB and CBX5 dissociation from chromosome arms. Promotes the repair of DNA double-strand breaks through the homologous recombination pathway. |
| Protein Name | Pogo Transposable Element With Znf DomainSuppressor Of Hairy Wing Homolog 5Zinc Finger Protein 280eZinc Finger Protein 635 |
| Database Links | |
| Cellular Localisation | NucleusChromosomeCytoplasmAccording To Some AuthorsIt Is Not Localized To Mitotic ChromatinRecruited To Trimethylated 'Lys-9' Of Histone H3 (H3k9me3) |
| Alternative Antibody Names | Anti-Pogo Transposable Element With Znf Domain antibodyAnti-Suppressor Of Hairy Wing Homolog 5 antibodyAnti-Zinc Finger Protein 280e antibodyAnti-Zinc Finger Protein 635 antibodyAnti-POGZ antibodyAnti-KIAA0461 antibodyAnti-SUHW5 antibodyAnti-ZNF280E antibodyAnti-ZNF635 antibodyAnti-Nbla00003 antibody |
Information sourced from Uniprot.org