350043 | Alpha-MSH Peptide Quimigen Portugal

Synthetic Peptide

Cat. No.

350043

Unit

5 mg

Description

MSH (melanocyte-stimulating hormone), produced by the pituitary gland, regulates the pigmentation of the skin by increasing melanin production in melanocytes. Alpha-MSH corresponds to aa 138-150 of corticotropin precursor (pro-opiomelanocortin, POMC). Alpha-MSH is an endogenous melanocortin receptor agonist (Ki values are 0.12, 31, 660 and 5700 nM for MC1, MC3, MC4 and MC5 receptors respectively). Alpha-MSH is an anti-inflammatory peptide which antagonizes proinflammatory mediators, including TNF-alpha, IL-6 and NO, and induces anti-inflammatory cytokine IL-10. It also inhibits food intake and induces penole erections following i.c.v. administration.

Spec Container

Datasheet

Format

Each vial contains 5 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.

Alternate Names

Alpha-MSH; melanotropin alpha; melanotropin hormone; corticotropin-lipotropin; pro-opiomelanocortin; POMC

Accession No.

P01189

1664.9 g/mol

Sequence

Human: Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2 or Ac-SYSMEHFRWGKPV-NH2

Composition

C77H109N21O19S1

Purity

Purity > 95% by HPLC

Solubility

Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.

Storage

Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.

For research use only, not for diagnostic or therapeutic procedures.

Alpha-MSH Peptide

Referencia 350043

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Marca : Abbiotec

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Spec Container