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> alpha 1 Antichymotrypsin (SERPINA3) (NM_001085) Human Recombinant Protein

alpha 1 Antichymotrypsin (SERPINA3) (NM_001085) Human Recombinant Protein

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Referencia TP720681

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alpha 1 Antichymotrypsin (SERPINA3) (NM_001085) Human Recombinant Protein

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SKU
TP720681
Purified recombinant protein of Human serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 (SERPINA3)
 

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Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
His24-Ala423
Tag C-His
Predicted MW 46.33 kDa
Concentration lot specific
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a 0.2 um filtered solution of 20mM HEPES, 150mM NaCl, pH 7.5.
Endotoxin Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
Reconstitution Method Always centrifuge tubes before opening. Do not mix by vortex or pipetting. Dissolve the lyophilized protein in ddH2O. It is not recommended to reconstitute a concentration less than 100 µg/ml. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Shipping Ambient
Reference Data
RefSeq NP_001076
Locus ID 12
UniProt ID P01011
Cytogenetics 14q32.13
RefSeq Size 1629
RefSeq ORF 1269
Synonyms AACT; ACT; GIG24; GIG25
Summary The protein encoded by this gene is a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. This gene is one in a cluster of serpin genes located on the q arm of chromosome 14. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease. provided by RefSeq, Jun 2020
Protein Categories Intracellular Proteins, Secreated Proteins
Protein Families Druggable Genome, Secreted Protein
FAQs
  • Protein FAQs
SDS
SKU Description Size
LC421268 Lyophilized SERPINA3 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
LY421268 Transient overexpression lysate of serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 (SERPINA3) (as WB positive control) 100 ug

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