ACCN1 Antibody - middle region
Referencia OAAB05805
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Marca : Aviva Systems Biology
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ACCN1 Antibody - middle region (OAAB05805)
| Datasheets/Manuals | Printable datasheet for ACCN1 Antibody - middle region (OAAB05805) |
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| Predicted Species Reactivity | Human|Mouse|Rat |
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| Product Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Clonality | Polyclonal |
| Isotype | Rabbit Ig |
| Host | Rabbit |
| Application | FC,IHC-P,WB |
| Reconstitution and Storage | Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Immunogen | This ACCN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 120-148 amino acids from the Central region of human ACCN1. |
| Predicted Homology Based on Immunogen Sequence | Human |
| Concentration | Approximately 0.5mg/ml. Actual concentration varies with each lot. |
| Sample Type Confirmation | ACCN1 is strongly supported by BioGPS gene expression data to be expressed in NCI-H460 |
| Application Info | WB: 1:1000 IHC-P: 1:50~100 FC: 1:10~50 |
| Gene Symbol | Asic2|ASIC2 |
|---|---|
| Gene Full Name | acid sensing ion channel subunit 2|acid-sensing (proton-gated) ion channel 2 |
| Alias Symbols | Acc, ACCN, ACCN1, ACIC2, acid sensing (proton gated) ion channel 2, acid-sensing (proton-gated) ion channel 2, acid-sensing ion channel 2, acid-sensing proton-gated ion channel 2 short variant MDEG2, amiloride-sensitive brain sodium channel, amiloride-sensitive brain sodium channel 2, amiloride-sensitive cation channel 1, neuronal, amiloride-sensitive cation channel 1, neuronal (degenerin), Amiloride-sensitive cation channel neuronal 1, ASIC2a, BNa, BNaC1, BNaC1a, BNC, BNC1, BNC1k, brain sodium channel 1, degenerin, hBNaC1, mammalian degenerin homolog, MDEG, MDEG1, MDEG2, neuronal amiloride-sensitive cation channel 1. |
| NCBI Gene Id | 11418|25364|40 |
| Protein Name | Acid-sensing ion channel 2|acid-sensing ion channel 2 isoform MDEG1 [Homo sapiens]|acid-sensing ion channel 2 isoform MDEG2 [Homo sapiens] |
| Description of Target | Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Also permeable for Li(+) and K(+). Activation by an extracellular pH drop is followed by a rapid pH-independent inactivation. Heteromeric channel assembly seems to modulate channel properties.|Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Also permeable for Li(+) and K(+). Generates a biphasic current with a fast inactivating and a slow sustained phase. Heteromeric channel assembly seems to modulate. |
| Uniprot ID | Q16515|Q62962|Q925H0 |
| Protein Accession # | https://www.ncbi.nlm.nih.gov/protein/NP_001085.2,NP_899233.1 |
| Molecular Weight | 57709 |