IL-6 receptor

IL-6 receptor

Cat# 516732-200ug

Size : 200ug

Brand : US Biological

Contact local distributor :


Phone : +1 850 650 7790


Host
rabbit

Isotype
IgG,k

Clone Number
rhPM-1 (Tocilizumab)

Grade
Affinity Purified

Applications
E

Shipping Temp
Blue Ice

Storage Temp
-20°C

IL6R; MRA; atlizumab
Recombinant monoclonal antibody to IL-6 receptor. Manufactured using Recombinant Platform with variable regions (i.e. specificity) from the therapeutic antibody rhPM-1 (Tocilizumab).

The IL6 receptor is a protein complex consisting of an IL-6 receptor subunit (IL6R) and interleukin 6 signal transducer Glycoprotein 130. Interleukin 6 (IL6) is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response.

Applications:
Suitable for use in ELISA. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Product Type
Mab

Isotype
IgG,k

Clone No
rhPM-1 (Tocilizumab)

Host
rabbit

Source
human

Concentration
~1mg/ml

Form
Supplied as a liquid in PBS, 0.02% Proclin 300.

Purity
Purified by Protein A affinity chromatography.

Immunogen
CDR grafting of mouse AUK 12-20 antibody onto a human framework regions.

Specificity
Recognizes human IL-6 receptor. Tocilizumab binds specifically to both the membrane bound and soluble forms of human IL-6R.


Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.