Prazosin Hydrochloride
Cat# 217694-500mg
Size : 500mg
Brand : US Biological
Contact local distributor :
Phone : +1 850 650 7790
Grade
Highly PurifiedShipping Temp
Blue IceStorage Temp
-20°C[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-furanylmethanone Hydrochloride; 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonxyl)|piperazine Hydrochloride; Adversuten; Adverszuten; Alpress LP; Furazosin; Lentopres; NSC 292810; Peripress; Terazosin EP Impurity K
Prazosin Hydrochloride (Terazosin EP Impurity K) is an antihypertensive. α1-Adrenergic blocker. Prazosin hydrochloride, a quinazole derivative, is a very potent and highly selective antagonist for apha-1-adrenoceptors (affinity for alpha-1 is about 1000-fold greater than for alpha-2 receptors). Mainly used as a clinic vasodilator for blood pressure control without increasing the heart rate or significantly impairing sympathetic functions. Has also been used clinically to treat anxiety, PTSD, and panic disorder. An excellent candidate for research studying brain functions mediated through alpha-1-adrenergic receptors, such as reward, pleasure, aggression, fear, anxiety, and addiction.
CAS Number:
19237-84-4
Free Base: 19216-56-9
Free Base: 19216-56-9
Molecular Formula:
C₁₉H₂₂ClN₅O₄
Molecular Weight:
419.86
Appearance:
White to Off-White Solid
Purity:
As reported
Melting Point:
>260°C (dec.)
Solubility:
DMSO, Methanol, Water, Slightly soluble (<1mg/ml) in ethanol.
Primary Target:
→1-adrenoceptors
Primary Target Ki:
0.17, 0.26, and 0.07 for →1a, →1b, and →1d adrenoceptor, respectively.
Storage and Stability:
Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Purity
As reported
Concentration
Not determined
Form
White to Off-White Solid
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.