Leflunomide-d4 (5-Methylisoxazole-4-[4-trifluoromethylcarboxanilide]-d4)

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Cat# L1662-92D-1mg

Size : 1mg

Contact local distributor :

Phone : +1 850 650 7790

Brand : US Biological

Contact local distributor :

Phone : +1 850 650 7790

Grade

Highly Purified

Shipping Temp

Storage Temp

-20°C

5-Methylisoxazole-4-[4-trifluoromethylcarboxanilide]-d4;

An immunosuppressive. Inhibits T and B cell proliferation. Activity is attributed mainly to its metabolite, a malononitrile derivative, which is beleived to inhibit dihydroorotate dehydrogenase as well as several protein tyrosine kinases.

Source:

Synthetic

Purity:

~90%

Form:

Supplied as an off-white crystalline solid

Melting Point:

159-161°C

Solubility:

Chloroform, Methanol

Method for Determining Identity:

Proton NMR and Mass Spectroscopic Analysis.

TLC Conditions:

SiO2: Hexane: Ethyl Acetate; 3:2; Visualized with UV and KMnO4; Single spot; Rf=0.6.

Storage and Stability:

May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Important Note

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards