Deferoxamine Mesylate (NSC 644468)
Cat# 271301-5g
Size : 5g
Brand : US Biological
Grade
Highly PurifiedShipping Temp
RTStorage Temp
4°CN1-(5-aminopentyl)-N1-hydroxy-N4-[5-[[4-[[5-(acetylhydroxyamino)pentyl]amino]-1,4-dioxobutyl]hydroxyamino]pentyl]butanediamide Methanesulfonate; N-[5-[3-[(5-aminopentyl)hydroxycarbamoyl]propionamido]pentyl]-3-[[5-(N-hydroxyacetamido)pentyl]carbamoyl]propionohydroxamic Acid Methanesulfonate; Ba 33112; DFOM; DFX mesylate; Deferoxamine B mesylate; Deferoxamine methanesulfonate; Deferrioxamine B methanesulfonate; Desferal mesylate; Desferrioxamine B mesylate; Desferrioxamine methanesulfonate; NSC 644468
An iron chelator used for the treatment of acute iron intoxication and of chronic iron overload due to transfusion-dependent anemias. Has been shown to have anti-proliferative effects on vascular smooth muscle cells in vitro and in vivo and to arrest cells in the G1 phase. Induces apoptosis in HL-60 cells by chelating iron. In addition, it has been shown to have antioxidant properties and to protect cells against H₂O₂-induced damage.
Synonyms:
N1-(5-aminopentyl)-N1-hydroxy-N4-[5-[[4-[[5-(acetylhydroxyamino)pentyl]amino]-1,4-dioxobutyl]hydroxyamino]pentyl]butanediamide methanesulfonate; N-[5-[3-[(5-aminopentyl)hydroxycarbamoyl]propionamido]pentyl]-3-[[5-(N-hydroxyacetamido)pentyl]carbamoyl]propionohydroxamic acid methanesulfonate; Ba 33112; Desferrioxamine B mesylate
CAS No:
138-14-7
Molecular Formula:
C₂₅H₄₈N₆O₈·CH₄O₃S
Molecular Weight:
656.79
Appearance:
White to off-white powder
Purity:
≥95%
Melting Point:
120-125°C
Solubility:
DMSO (Slightly, Heated), Methanol (Slightly, Heated)
Storage and Stability:
Store at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards