Extracellular vesicles (EVs) bioengineered via a proprietary platform enable stable, non-perturbing incorporation of >130 membrane or luminal proteins while fully preserving endogenous biogenesis pathways, native protein topology, and canonical EV marker expression (CD63, CD81, CD9; negative for calnexin, GM130). Particle size distribution remains tightly controlled (median 60–70 nm), with purity and integrity validated by nano-flow cytometry, nanoparticle tracking analysis (NTA), and MISEV2018-compliant multimodal characterization (protein/particle ratio, morphology by cryo-TEM, functional topology by ligand-binding assays).
To facilitate high-impact EV research, a 15% discount is applied to the featured portfolio from November 13, 2025, to January 9, 2026. All EVs are derived from HEK293T cells, purified to extra-pure grade (>95 % EV recovery, <5 % non-EV contaminants), and formulated in PBS + 10 µg/mL BSA for documented stability at +4 °C.
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15% OFF |
Standard EVs are native EVs, produced by non-modified cells. These EVs are interesting tools that can be used for data normalisation, EV instrument calibration or as a control, either positive or negative, in EV quality controls, EV characterisation, functional assays, etc.
| Product | Format | Particles | Link |
|---|---|---|---|
| HEK293T Standard EVs | 50 µg | ≥ 1 × 10¹⁰ | Order |
| HEK293T Standard EVs | 100 µg | ≥ 2 × 10¹⁰ | Order |
Labelled EVs bioengineered with internal cargoes are customised using Ciloa technology which does not overexpress and has no interaction with regular EV surface proteins like tetraspanins. These EVs can be used for data normalisation, purification process internal standard, instrument calibration and cell fluorescence imaging.
| Product | Format | Particles | Link |
|---|---|---|---|
| mCerulean EVs | 30 µg | ≥ 1 × 10¹⁰ | Order |
| Nluc EVs | 50 µg | ≥ 1 × 10¹⁰ | Order |
| EGFP EVs | 50 µg | ≥ 1 × 10¹⁰ | Order |
| CyOFP1 EVs | 30 µg | ≥ 1 × 10¹⁰ | Order |
100% fully native membrane proteins embedded with their right topology into EV membrane.
EVs can harbour any kind of protein like:
- G-protein coupled receptors (GPCRs): CCR-10 EVs and CCR-7 EVs
- Kinase receptors: ALK-2 EVs, MISRII EVs, ALK-4 EVs
These EVs can be used to study molecular interactions with ligands, specific antibodies or small molecules.
| Product | Target | Format | Particles | Link |
|---|---|---|---|---|
| CCR-10 EVs | CCR10 | 30 µg | ≥ 5 × 10⁹ | Order |
| CCR-7 EVs | CCR7 | 50 µg | ≥ 1 × 10¹⁰ | Order |
| CCR-7 EVs | CCR7 | 100 µg | ≥ 2 × 10¹⁰ | Order |
| ALK-2 EVs | ACVR1 | 50 µg | ≥ 1 × 10¹⁰ | Order |
| MISRII EVs | AMHR2 | 50 µg | ≥ 8 × 10⁹ | Order |
| ALK-4 EVs | ACVR1B | 50 µg | ≥ 1 × 10¹⁰ | Order |
Secure your MISEV-compliant EVs at 15% discount before January 9, 2026.
Shop NowNeed custom EVs or bulk quantities? Contact tech@quimigen.pt
