FBS and serum alternatives for optimized cell culture workflows

 

Discover FBS, reduced-serum, xeno-free and fully defined alternatives to improve performance, reproducibility and cost control in cell culture

Fetal Bovine Serum (FBS) remains one of the most widely used supplements for cell culture, but many laboratories are now looking for solutions that offer better reproducibility, improved standardization, reduced batch-to-batch variability or alternatives to animal-derived serum.

Quimigen offers a complete portfolio of FBS and serum alternatives to help you select the most appropriate supplement for your cell culture workflow, from standard research applications to more defined, xeno-free or serum-free culture conditions.

Explore our solutions for cell culture supplementation

Standard FBS

Standard Fetal Bovine Serum is a reliable and versatile supplement for a broad range of cell culture applications. It is rich in growth-promoting components and suitable for many standard R&D workflows.

FBS Stable

For laboratories seeking more consistent results, FBS Stable is designed to reduce batch-to-batch variability while maintaining reliable cell growth performance. It is particularly relevant for long-term studies, multi-site projects or workflows where lot reservation can be a constraint.

FBS 2.0

FBS 2.0 is a next-generation serum supplement developed to provide a more defined and reproducible alternative to standard FBS. With reduced serum content and added growth-promoting components, it helps support robust cell growth while reducing the impact of undefined serum variability.

Bovine and other animal sera

Depending on your application and cell type, bovine serum alternatives such as newborn calf serum, calf serum or adult bovine serum may be suitable for robust cell lines, short-term culture or specific assay formats. Quimigen also provides sera from other animal species for applications such as immunohistochemistry blocking, veterinary research and autologous culture systems.

Human serum : Human serum can be a relevant alternative for researchers working with sensitive human cells, including macrophages, lymphocytes and other primary human cell types. Human AB serum is particularly useful when a more human-like culture environment is required.

XerumFree™: XerumFree™ is a fully defined, animal-free and human-component-free cell culture supplement designed to replace serum in a wide range of cell culture applications. It helps reduce lot-to-lot variability and avoids undefined serum components that may interfere with experimental outcomes.

UltraGRO™: UltraGRO™ is a xeno-free, animal serum-free human platelet lysate supplement designed to replace FBS for the expansion of mesenchymal stem cells, including bone marrow-, adipose tissue- and umbilical cord-derived MSCs. RUO and GMP-grade options are available depending on your workflow and regulatory requirements. 

SEREXISTM : is a defined, homogeneous serum replacement that delivers consistent FBS-like performance across multiple cell lines. Its controlled composition ensures high reproducibility and process control, while enabling direct, seamless substitution for FBS at standard concentrations—no protocol changes required. Combining efficacy, safety, and reliability, SEREXISTM is a versatile, ready-to-use alternative for robust cell culture applications.

Why choose Quimigen for FBS and alternatives?

Our team can help you compare serum origin, batch consistency, regulatory expectations, cell type compatibility, budget constraints and animal-free requirements. Whether you need standard FBS, a more reproducible serum, a reduced-serum solution, human serum, xeno-free supplementation or a fully defined alternative, Quimigen can help you identify the right option for your research.

Need support selecting the best supplement for your cells?

Contact our technical team to discuss your application, cell type and performance requirements.