stabilin1 (STAB1) (C-term) Goat Polyclonal Antibody

Cat# AP33007PU-N

Size : 100ug

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stabilin1 (STAB1) (C-term) Goat Polyclonal Antibody

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AP33007PU-N
stabilin1 (STAB1) (C-term) goat polyclonal antibody, Aff - Purified
 
Specifications
Product Data
Application ELISA, IHC
Recommended Dilution Peptide ELISA: 1/8000 (Detection Limit).
Immunohistochemistry on Paraffin Sections: 3-5 µg/ml. In paraffin embedded Human Spleen shows endothelial staining.
Reactivity Bovine, Canine, Human, Porcine
Antibody Host Goat
Clonality Polyclonal
Immunogen Peptide with sequence C-DFPDTQRILTVK, from the C Terminus of the protein sequence according to NP_055951.2.
Specificity This antibody recognizes Stabilin-1 at C-term.
Buffer Tris saline, pH~7.3
State: Aff - Purified
State: Liquid purfied Ig fraction
Stabilizer: 0.5% BSA
Preservative: 0.02% Sodium Azide
Concentration lot specific
Purification Antigen Affinity Chromatography
Conjugation Unconjugated
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Gene Name stabilin 1
Database Link
Background Stabilin-1 is a large transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 16 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to endocytose ligands such as low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein rapidly cycles between the plasma membrane and early endosomes (Entrez gene 23166). Cellular localization: Membrane; Single-pass type I membrane protein.
Synonyms Stabilin-1, FEEL1, FEEL-1, CLEVER-1, KIAA0246
Reference Data
Protein Categories Growth Factors, Membrane Proteins

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