SRY Capture Antibody
Cat# OAOA21638
Size : 100µg
Brand : Aviva Systems Biology
Contact local distributor :
Phone : +1 850 650 7790
SRY Capture Antibody (OAOA21638)
| Datasheets/Manuals | Printable datasheet for SRY Capture Antibody (OAOA21638) |
|---|
| Predicted Species Reactivity | Human |
|---|---|
| Product Format | Stored in PBS (pH 7.4) containing 0.05% sodium azide and up to 5% trehalose |
| Clonality | Monoclonal |
| Clone | OTI1H10 |
| Isotype | IgG1 |
| Host | Mouse |
| Application | MlpxA |
| Reconstitution and Storage | -20°C |
| Immunogen | Full length human recombinant protein of human SRY (NM_005986) produced in HEK293T cell. |
| Concentration | 0.5 mg/ml |
| Dilution | 1:100 - 1:1000 |
| Description | SRY mouse monoclonal capture antibody, validated for Luminex assays |
| Gene Symbol | SRY |
|---|---|
| Gene Full Name | sex determining region Y |
| Alias Symbols | essential protein for sex determination in human males, sex-determining region on Y, sex-determining region Y protein, SRXX1, SRXY1, TDF, TDY, Testis-determining factor, testis-determining factor on Y, truncated sex-determining region Y protein. |
| NCBI Gene Id | 6736 |
| Protein Name | Homo sapiens sex determining region Y (SRY), mRNA|Sex-determining region Y protein |
| Description of Target | Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells (By similarity). In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity). Involved in different aspects of gene regulation including promoter activation or repression (By similarity). Promotes DNA bending. SRY HMG box recognizes DNA by partial intercalation in the minor groove. Also involved in pre-mRNA splicing. Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'. |
| Uniprot ID | Q05066 |
| Protein Accession # | NP_003131 |
| Nucleotide Accession # | https://www.ncbi.nlm.nih.gov/nuccore/NM_003140 |
