Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human glioma tissue, showing membrane localization using SNCA monoclonal antibody, clone 2B2D1 (Cat # MAB10407).
Western Blot (Recombinant protein)
Western blot analysis using SNCA monoclonal antibody, clone 2B2D1 (Cat # MAB10407) against truncated SNCA recombinant protein.
- Specifications
Product Description
Mouse monoclonal antibody raised against recombinant SNCA.
Immunogen
Recombinant protein corresponding to human SNCA.
Host
Mouse
Reactivity
Human
Form
Liquid
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunohistochemistry (1:200-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascites (0.03% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human glioma tissue, showing membrane localization using SNCA monoclonal antibody, clone 2B2D1 (Cat # MAB10407).Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Western blot analysis using SNCA monoclonal antibody, clone 2B2D1 (Cat # MAB10407) against truncated SNCA recombinant protein. - Gene Info — SNCA
Entrez GeneID
6622Gene Name
SNCA
Gene Alias
MGC110988, NACP, PARK1, PARK4, PD1
Gene Description
synuclein, alpha (non A4 component of amyloid precursor)
Gene Ontology
HyperlinkGene Summary
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000161559|OTTHUMP00000161561|alpha synuclein|alpha-synuclein|alpha-synuclein, isoform NACP140|non A-beta component of AD amyloid|non A4 component of amyloid
- Interactomes
- Diseases