Reverse transcriptase-IN-3

Cat# NB-64-40281-100mg

Size : 100mg

Brand : Neo Biotech

Contact local distributor :


Phone : +1 850 650 7790

Reverse transcriptase-IN-3

Catalog No. T72203 Copy Product Info
Reverse transcriptase-IN-3, a pyrimidine-5-carboxamide derivative, functions as an inhibitor of HIV-1, demonstrating potent activity against both wild-type and mutant strains of HIV-1.

Reverse transcriptase-IN-3

Copy Product Info

Reverse transcriptase-IN-3, a pyrimidine-5-carboxamide derivative, functions as an inhibitor of HIV-1, demonstrating potent activity against both wild-type and mutant strains of HIV-1.

Reverse transcriptase-IN-3

Product Introduction

Bioactivity
Description
Reverse transcriptase-IN-3, a pyrimidine-5-carboxamide derivative, functions as an inhibitor of HIV-1, demonstrating potent activity against both wild-type and mutant strains of HIV-1.
Targets&IC50
HIV IIIB:8 nM (EC50), E138K:0.734 μM (EC50), Y181C:45 nM (EC50), L100I:65 nM (EC50), Y188L:35 nM (EC50), HIV-1 (F227L+V106A):34 nM (EC50), K103N:9 nM (EC50), HIV-1 (RES056):42 nM (EC50)
Chemical Properties
Molecular Weight561.66
FormulaC28H31N7O4S
SmilesCC1=CC(=CC(=C1OC2=NC(=NC=C2C(=O)N)NC3CCN(CC3)C4=CC=C(C=C4)NS(=O)(=O)C5CC5)C)C#N
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Citations